什么是血小板减少症？血小板减少症的病因是什么？

印度代购提示您，什么是血小板减少症？

外周血液中血小板数量异常减少(采用血小板直接计数法时低于10^10/L)的现象。通常情况下，血小板<50×10^9/L时，即存在皮肤、黏膜出血的危险性;<20×10^9/L时，有自发性出血的高度危险性;<10×10^9/L时则有极高度危险性。

An abnormal decrease in the number of platelets in peripheral blood (below 10^10/L by direct platelet counting). Under normal circumstances, when platelet <50×10^9/L, that is, there is the risk of skin and mucosal bleeding; <20×10^9/L, there is a high risk of spontaneous bleeding; <10×10^9/L is extremely dangerous.

印度代购提示您，血小板减少症的病因是什么？

1.血小板生成不足：

　　可见于某些病理情况如再生障碍性贫血(AA)、急性白血病(AL)以及感染等时，或者由于某些毒物或药物如苯、二甲苯、环磷酰胺等的有害作用，骨髓内巨核细胞的增殖或生长成熟发生障碍，可引起血小板生成不足和数量减少。

2.血小板破坏过多：

　　见于某些药物如磺胺、氯霉素、安基比林等的作用或感染时，通过免疫机制，体内产生抗血小板抗体，致使血小板破坏过多和数量减少。还可见于原发免疫性血小板减少症(ITP)、弥散性血管内凝血(DIC)、血栓性血小板减少症(TTP)、肝素诱发的血小板减少症(HIT)、系统性红斑狼疮(SLE)、HIV-1相关血小板减少症。

In some drugs such as sulfanilamide, chloramphenicol, angelpyrine and other effects or infection, through the immune mechanism, the body produces anti-platelet antibodies, resulting in excessive platelet damage and the number of reduced. It can also be seen in primary immune thrombocytopenia (ITP), disseminated intravascular coagulation (DIC), thrombotic thrombocytopenia (TTP), heparin-induced thrombocytopenia (HIT), systemic lupus erythematosus (SLE), and HIV-1 associated thrombocytopenia.